Dual-mode of insulin action controls GLUT4 vesicle exocytosis

Insulin releases an intracellular brake and promotes fusion pore expansion to translocate GLUT4 vesicles, and switches vesicle trafficking between distinct exocytic circuits.

Bibliographic Details
Main Authors: Xu, Yingke, Rubin, Bradley R., Orme, Charisse M., Karpikov, Alexander, Yu, Chenfei, Bogan, Jonathan S., Toomre, Derek K.
Format: Online
Language:English
Published: The Rockefeller University Press 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166865/