Involvement of interleukin-21 in the regulation of colitis-associated colon cancer
IL-21 expression is increased in the gut of patients with colitis-associated colon cancer, and genetic ablation or antibody neutralization of IL-21 reduces tumor size and inflammation in mice treated with dextran sulfate sodium and azoxymethane.
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
The Rockefeller University Press
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201207/ |