Molecular Targets of TRAIL-Sensitizing Agents in Colorectal Cancer

Tumor necrosis factor (TNF)-related apoptosis inducing ligand (TRAIL), a member of the TNF superfamily, interacts with its functional death receptors (DRs) and induces apoptosis in a wide range of cancer cell types. Therefore, TRAIL has been considered as an attractive agent for cancer therapy. Howe...

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Bibliographic Details
Main Authors: Stolfi, Carmine, Pallone, Francesco, Monteleone, Giovanni
Format: Online
Language:English
Published: Molecular Diversity Preservation International (MDPI) 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430210/