Involvement of interleukin-21 in the regulation of colitis-associated colon cancer

IL-21 expression is increased in the gut of patients with colitis-associated colon cancer, and genetic ablation or antibody neutralization of IL-21 reduces tumor size and inflammation in mice treated with dextran sulfate sodium and azoxymethane.

Bibliographic Details
Main Authors:	Stolfi, Carmine, Rizzo, Angelamaria, Franzè, Eleonora, Rotondi, Angela, Fantini, Massimo Claudio, Sarra, Massimiliano, Caruso, Roberta, Monteleone, Ivan, Sileri, Pierpaolo, Franceschilli, Luana, Caprioli, Flavio, Ferrero, Stefano, MacDonald, Thomas T., Pallone, Francesco, Monteleone, Giovanni
Format:	Online
Language:	English
Published:	The Rockefeller University Press 2011
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201207/

id	pubmed-3201207
recordtype	oai_dc
spelling	pubmed-32012072012-04-24 Involvement of interleukin-21 in the regulation of colitis-associated colon cancer Stolfi, Carmine Rizzo, Angelamaria Franzè, Eleonora Rotondi, Angela Fantini, Massimo Claudio Sarra, Massimiliano Caruso, Roberta Monteleone, Ivan Sileri, Pierpaolo Franceschilli, Luana Caprioli, Flavio Ferrero, Stefano MacDonald, Thomas T. Pallone, Francesco Monteleone, Giovanni Article IL-21 expression is increased in the gut of patients with colitis-associated colon cancer, and genetic ablation or antibody neutralization of IL-21 reduces tumor size and inflammation in mice treated with dextran sulfate sodium and azoxymethane. The Rockefeller University Press 2011-10-24 /pmc/articles/PMC3201207/ /pubmed/21987656 http://dx.doi.org/10.1084/jem.20111106 Text en © 2011 Stolfi et al. This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Stolfi, Carmine Rizzo, Angelamaria Franzè, Eleonora Rotondi, Angela Fantini, Massimo Claudio Sarra, Massimiliano Caruso, Roberta Monteleone, Ivan Sileri, Pierpaolo Franceschilli, Luana Caprioli, Flavio Ferrero, Stefano MacDonald, Thomas T. Pallone, Francesco Monteleone, Giovanni
spellingShingle	Stolfi, Carmine Rizzo, Angelamaria Franzè, Eleonora Rotondi, Angela Fantini, Massimo Claudio Sarra, Massimiliano Caruso, Roberta Monteleone, Ivan Sileri, Pierpaolo Franceschilli, Luana Caprioli, Flavio Ferrero, Stefano MacDonald, Thomas T. Pallone, Francesco Monteleone, Giovanni Involvement of interleukin-21 in the regulation of colitis-associated colon cancer
author_facet	Stolfi, Carmine Rizzo, Angelamaria Franzè, Eleonora Rotondi, Angela Fantini, Massimo Claudio Sarra, Massimiliano Caruso, Roberta Monteleone, Ivan Sileri, Pierpaolo Franceschilli, Luana Caprioli, Flavio Ferrero, Stefano MacDonald, Thomas T. Pallone, Francesco Monteleone, Giovanni
author_sort	Stolfi, Carmine
title	Involvement of interleukin-21 in the regulation of colitis-associated colon cancer
title_short	Involvement of interleukin-21 in the regulation of colitis-associated colon cancer
title_full	Involvement of interleukin-21 in the regulation of colitis-associated colon cancer
title_fullStr	Involvement of interleukin-21 in the regulation of colitis-associated colon cancer
title_full_unstemmed	Involvement of interleukin-21 in the regulation of colitis-associated colon cancer
title_sort	involvement of interleukin-21 in the regulation of colitis-associated colon cancer
description	IL-21 expression is increased in the gut of patients with colitis-associated colon cancer, and genetic ablation or antibody neutralization of IL-21 reduces tumor size and inflammation in mice treated with dextran sulfate sodium and azoxymethane.
publisher	The Rockefeller University Press
publishDate	2011
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201207/
_version_	1611483497210314752

Involvement of interleukin-21 in the regulation of colitis-associated colon cancer

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