Involvement of interleukin-21 in the regulation of colitis-associated colon cancer

Involvement of interleukin-21 in the regulation of colitis-associated colon cancer

IL-21 expression is increased in the gut of patients with colitis-associated colon cancer, and genetic ablation or antibody neutralization of IL-21 reduces tumor size and inflammation in mice treated with dextran sulfate sodium and azoxymethane.

Bibliographic Details
Main Authors: Stolfi, Carmine, Rizzo, Angelamaria, Franzè, Eleonora, Rotondi, Angela, Fantini, Massimo Claudio, Sarra, Massimiliano, Caruso, Roberta, Monteleone, Ivan, Sileri, Pierpaolo, Franceschilli, Luana, Caprioli, Flavio, Ferrero, Stefano, MacDonald, Thomas T., Pallone, Francesco, Monteleone, Giovanni
Format: Online
Language:English
Published: The Rockefeller University Press 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201207/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201207/

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