IL-21 expression is increased in the gut of patients with colitis-associated colon cancer, and genetic ablation or antibody neutralization of IL-21 reduces tumor size and inflammation in mice treated with dextran sulfate sodium and azoxymethane.
Bibliographic Details
| Main Authors: |
Stolfi, Carmine,
Rizzo, Angelamaria,
Franzè, Eleonora,
Rotondi, Angela,
Fantini, Massimo Claudio,
Sarra, Massimiliano,
Caruso, Roberta,
Monteleone, Ivan,
Sileri, Pierpaolo,
Franceschilli, Luana,
Caprioli, Flavio,
Ferrero, Stefano,
MacDonald, Thomas T.,
Pallone, Francesco,
Monteleone, Giovanni |
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| Format: | Online
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| Language: | English |
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| Published: |
The Rockefeller University Press
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201207/
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