Antigen-dependent Proliferation of CD4+ CD25+ Regulatory T Cells In Vivo

Antigen-dependent Proliferation of CD4+ CD25+ Regulatory T Cells In Vivo

The failure of CD25+ regulatory T cells (Tregs) to proliferate after T cell receptor (TCR) stimulation in vitro has lead to their classification as naturally anergic. Here we use Tregs expressing a transgenic TCR to show that despite anergy in vitro, Tregs proliferate in response to immunization in...

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Bibliographic Details
Main Authors:	Walker, Lucy S.K., Chodos, Anna, Eggena, Mark, Dooms, Hans, Abbas, Abul K.
Format:	Online
Language:	English
Published:	The Rockefeller University Press 2003
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194065/

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