Direct Expansion of Functional CD25+ CD4+ Regulatory T Cells by Antigen-processing Dendritic Cells

An important pathway for immune tolerance is provided by thymic-derived CD25+ CD4+ T cells that suppress other CD25− autoimmune disease–inducing T cells. The antigen-presenting cell (APC) requirements for the control of CD25+ CD4+ suppressor T cells remain to be identified, hampering their study in...

Full description

Bibliographic Details
Main Authors: Yamazaki, Sayuri, Iyoda, Tomonori, Tarbell, Kristin, Olson, Kara, Velinzon, Klara, Inaba, Kayo, Steinman, Ralph M.
Format: Online
Language:English
Published: The Rockefeller University Press 2003
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194081/