Continuous control of autoimmune disease by antigen-dependent polyclonal CD4+CD25+ regulatory T cells in the regional lymph node
This study investigated the unresolved issue of antigen-dependency and antigen-specificity of autoimmune disease suppression by CD4+CD25+ T cells (T regs). Based on autoimmune ovarian disease (AOD) in day 3 thymectomized (d3tx) mice and polyclonal T regs expressing the Thy1.1 marker, we determined:...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2005
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212949/ |