HSP70 Enhances Immunosuppressive Function of CD4+CD25+FoxP3+ T Regulatory Cells and Cytotoxicity in CD4+CD25− T Cells

HSP70 Enhances Immunosuppressive Function of CD4+CD25+FoxP3+ T Regulatory Cells and Cytotoxicity in CD4+CD25− T Cells

Human CD4+CD25+FoxP3+ T regulatory cells (Tregs) control effector T cells and play a central role in peripheral tolerance and immune homeostasis. Heat shock protein 70 (HSP70) is a major immunomodulatory molecule, but its effect on the functions of Tregs is not well understood. To investigate target...

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Bibliographic Details
Main Authors: Wachstein, Julian, Tischer, Sabine, Figueiredo, Constanca, Limbourg, Anne, Falk, Christine, Immenschuh, Stephan, Blasczyk, Rainer, Eiz-Vesper, Britta
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530531/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530531/

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