The role of regulatory T cells in antigen-induced arthritis: aggravation of arthritis after depletion and amelioration after transfer of CD4+CD25+ T cells

It is now generally accepted that CD4+CD25+ Treg cells play a major role in the prevention of autoimmunity and pathological immune responses. Their involvement in the pathogenesis of chronic arthritis is controversial, however, and so we examined their role in experimental antigen-induced arthritis...

Full description

Bibliographic Details
Main Authors: Frey, Oliver, Petrow, Peter K, Gajda, Mieczyslaw, Siegmund, Kerstin, Huehn, Jochen, Scheffold, Alexander, Hamann, Alf, Radbruch, Andreas, Bräuer, Rolf
Format: Online
Language:English
Published: BioMed Central 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1065322/