Tubulin inhibitors targeting the colchicine binding site: a perspective of privileged structures
The vital roles of microtubule in mitosis and cell division make it an attractive target for antitumor therapy. Colchicine binding site of tubulin is one of the most important pockets that have been focused on to design tubulin-destabilizing agents. Over the past few years, a large number of colchic...
Main Authors: | Li, Wenlong, Sun, Honghao, Xu, Shengtao, Zhu, Zheying, Xu, Jinyi |
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Format: | Article |
Language: | English |
Published: |
Future Science
2017
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Online Access: | http://eprints.nottingham.ac.uk/46454/ http://eprints.nottingham.ac.uk/46454/ http://eprints.nottingham.ac.uk/46454/ http://eprints.nottingham.ac.uk/46454/1/FMC-2017-0100-accepted.pdf |
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