Quick and Simple Detection Technique to Assess the Binding of Antimicrotubule Agents to the Colchicine-Binding Site
Development of antimitotic binding to the colchicine-binding site for the treatment of cancer is rapidly expanding. Numerous antimicrotubule agents are prepared every year, and the determination of their binding affinity to tubulin requires the use of purified tubulins and radiolabeled ligands. Such...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
BioMed Central
2010
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055821/ |