Cross Reactive Material 197 glycoconjugate vaccines contain privileged conjugation sites

Production of glycoconjugate vaccines involves the chemical conjugation of glycans to an immunogenic carrier protein such as Cross-Reactive-Material-197 (CRM197). Instead of using glycans from natural sources recent vaccine development has been focusing on the use of synthetically defined minimal ep...

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Bibliographic Details
Main Authors: Möginger, Uwe, Resemann, Anja, Martin, Christopher E., Parameswarappa, Sharavathi, Govindan, Subramanian, Wamhoff, Eike-Christian, Broecker, Felix, Suckau, Detlev, Pereira, Claney Lebev, Anish, Chakkumkal, Seeberger, Peter H., Kolarich, Daniel
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740906/