Tubulin inhibitors targeting the colchicine binding site: a perspective of privileged structures

The vital roles of microtubule in mitosis and cell division make it an attractive target for antitumor therapy. Colchicine binding site of tubulin is one of the most important pockets that have been focused on to design tubulin-destabilizing agents. Over the past few years, a large number of colchic...

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Bibliographic Details
Main Authors: Li, Wenlong, Sun, Honghao, Xu, Shengtao, Zhu, Zheying, Xu, Jinyi
Format: Article
Language:English
Published: Future Science 2017
Online Access:http://eprints.nottingham.ac.uk/46454/
http://eprints.nottingham.ac.uk/46454/
http://eprints.nottingham.ac.uk/46454/
http://eprints.nottingham.ac.uk/46454/1/FMC-2017-0100-accepted.pdf