Acute myeloid leukaemia: a paradigm for the clonal evolution of cancer?

by Grove, Carolyn S., Vassiliou, George S.
Published 2014

Stella-Cre Mice are Highly Efficient Cre Deleters

by Liu, Hui, Wang, Wei, Chew, Su-Kit, Lee, Song-Choon, Li, Juan, Vassiliou, George S, Green, Tony, Futreal, P Andrew, Bradley, Allan, Zhang, Shujun, Liu, Pentao
Published 2011

Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice

by Vassiliou, George S., Cooper, Jonathan L., Rad, Roland, Li, Juan, Rice, Stephen, Uren, Anthony, Rad, Lena, Ellis, Peter, Andrews, Rob, Banerjee, Ruby, Grove, Carolyn, Wang, Wei, Liu, Pentao, Wright, Penny, Arends, Mark, Bradley, Allan
Published 2011

Leukemia-Associated Somatic Mutations Drive Distinct Patterns of Age-Related Clonal Hemopoiesis

by McKerrell, Thomas, Park, Naomi, Moreno, Thaidy, Grove, Carolyn S., Ponstingl, Hannes, Stephens, Jonathan, Crawley, Charles, Craig, Jenny, Scott, Mike A., Hodkinson, Clare, Baxter, Joanna, Rad, Roland, Forsyth, Duncan R., Quail, Michael A., Zeggini, Eleftheria, Ouwehand, Willem, Varela, Ignacio, Vassiliou, George S.
Published 2015

Capturing needles in haystacks: a comparison of B-cell receptor sequencing methods

by Bashford-Rogers, Rachael JM, Palser, Anne L, Idris, Saad F, Carter, Lisa, Epstein, Michael, Callard, Robin E, Douek, Daniel C, Vassiliou, George S, Follows, George A, Hubank, Mike, Kellam, Paul
Published 2014

A Genetic Progression Model of BrafV600E-Induced Intestinal Tumorigenesis Reveals Targets for Therapeutic Intervention

by Rad, Roland, Cadiñanos, Juan, Rad, Lena, Varela, Ignacio, Strong, Alexander, Kriegl, Lydia, Constantino-Casas, Fernando, Eser, Stefan, Hieber, Maren, Seidler, Barbara, Price, Stacey, Fraga, Mario F., Calvanese, Vincenzo, Hoffman, Gary, Ponstingl, Hannes, Schneider, Günter, Yusa, Kosuke, Grove, Carolyn, Schmid, Roland M., Wang, Wei, Vassiliou, George, Kirchner, Thomas, McDermott, Ultan, Liu, Pentao, Saur, Dieter, Bradley, Allan
Published 2013

Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia

by Picaud, Sarah, Leonards, Katharina, Lambert, Jean-Philippe, Dovey, Oliver, Wells, Christopher, Fedorov, Oleg, Monteiro, Octovia, Fujisawa, Takao, Wang, Chen-Yi, Lingard, Hannah, Tallant, Cynthia, Nikbin, Nikzad, Guetzoyan, Lucie, Ingham, Richard, Ley, Steven V., Brennan, Paul, Muller, Susanne, Samsonova, Anastasia, Gingras, Anne-Claude, Schwaller, Juerg, Vassiliou, George, Knapp, Stefan, Filippakopoulos, Panagis
Published 2016

A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia

by Tzelepis, Konstantinos, Koike-Yusa, Hiroko, De Braekeleer, Etienne, Li, Yilong, Metzakopian, Emmanouil, Dovey, Oliver M., Mupo, Annalisa, Grinkevich, Vera, Li, Meng, Mazan, Milena, Gozdecka, Malgorzata, Ohnishi, Shuhei, Cooper, Jonathan, Patel, Miten, McKerrell, Thomas, Chen, Bin, Domingues, Ana Filipa, Gallipoli, Paolo, Teichmann, Sarah, Ponstingl, Hannes, McDermott, Ultan, Saez-Rodriguez, Julio, Huntly, Brian J.P., Iorio, Francesco, Pina, Cristina, Vassiliou, George S., Yusa, Kosuke
Published 2016

A novel mouse model identifies cooperating mutations and therapeutic targets critical for chronic myeloid leukemia progression

by Giotopoulos, George, van der Weyden, Louise, Osaki, Hikari, Rust, Alistair G., Gallipoli, Paolo, Meduri, Eshwar, Horton, Sarah J., Chan, Wai-In, Foster, Donna, Prinjha, Rab K., Pimanda, John E., Tenen, Daniel G., Vassiliou, George S., Koschmieder, Steffen, Adams, David J., Huntly, Brian J.P.
Published 2015

Multiplexed pancreatic genome engineering and cancer induction by transfection-based CRISPR/Cas9 delivery in mice

by Maresch, Roman, Mueller, Sebastian, Veltkamp, Christian, Öllinger, Rupert, Friedrich, Mathias, Heid, Irina, Steiger, Katja, Weber, Julia, Engleitner, Thomas, Barenboim, Maxim, Klein, Sabine, Louzada, Sandra, Banerjee, Ruby, Strong, Alexander, Stauber, Teresa, Gross, Nina, Geumann, Ulf, Lange, Sebastian, Ringelhan, Marc, Varela, Ignacio, Unger, Kristian, Yang, Fengtang, Schmid, Roland M., Vassiliou, George S., Braren, Rickmer, Schneider, Günter, Heikenwalder, Mathias, Bradley, Allan, Saur, Dieter, Rad, Roland
Published 2016

Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

by Ju, Young Seok, Alexandrov, Ludmil B, Gerstung, Moritz, Martincorena, Inigo, Nik-Zainal, Serena, Ramakrishna, Manasa, Davies, Helen R, Papaemmanuil, Elli, Gundem, Gunes, Shlien, Adam, Bolli, Niccolo, Behjati, Sam, Tarpey, Patrick S, Nangalia, Jyoti, Massie, Charles E, Butler, Adam P, Teague, Jon W, Vassiliou, George S, Green, Anthony R, Du, Ming-Qing, Unnikrishnan, Ashwin, Pimanda, John E, Teh, Bin Tean, Munshi, Nikhil, Greaves, Mel, Vyas, Paresh, El-Naggar, Adel K, Santarius, Tom, Collins, V Peter, Grundy, Richard, Taylor, Jack A, Hayes, D Neil, Malkin, David, Foster, Christopher S, Warren, Anne Y, Whitaker, Hayley C, Brewer, Daniel, Eeles, Rosalind, Cooper, Colin, Neal, David, Visakorpi, Tapio, Isaacs, William B, Bova, G Steven, Flanagan, Adrienne M, Futreal, P Andrew, Lynch, Andy G, Chinnery, Patrick F, McDermott, Ultan, Stratton, Michael R, Campbell, Peter J
Published 2014