The impact of trisomy 21 on early human hematopoiesis

by Roy, Anindita, Cowan, Gillian, Vyas, Paresh, Roberts, Irene
Published 2013

Transient Abnormal Myelopoiesis and AML in Down Syndrome: an Update

by Bhatnagar, Neha, Nizery, Laure, Tunstall, Oliver, Vyas, Paresh, Roberts, Irene
Published 2016

Development of Real-Time Quantitative Polymerase Chain Reaction Assays to Track Treatment Response in Retinoid Resistant Acute Promyelocytic Leukemia

by Jovanovic, Jelena V., Rennie, Kristian, Culligan, Dominic, Peniket, Andrew, Lennard, Anne, Harrison, Justin, Vyas, Paresh, Grimwade, David
Published 2011

Uncoupling VEGFA Functions in Arteriogenesis and Hematopoietic Stem Cell Specification

by Leung, Amy, Ciau-Uitz, Aldo, Pinheiro, Philip, Monteiro, Rui, Zuo, Jie, Vyas, Paresh, Patient, Roger, Porcher, Catherine
Published 2013

Structural Basis for LMO2-Driven Recruitment of the SCL:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets

by El Omari, Kamel, Hoosdally, Sarah J., Tuladhar, Kapil, Karia, Dimple, Hall-Ponselé, Elisa, Platonova, Olga, Vyas, Paresh, Patient, Roger, Porcher, Catherine, Mancini, Erika J.
Published 2013

GATA1s induces hyperproliferation of eosinophil precursors in Down syndrome transient leukemia

by Maroz, Aliaksandra, Stachorski, Lena, Emmrich, Stephan, Reinhardt, Katarina, Xu, Jian, Shao, Zhen, Käbler, Sebastian, Dertmann, Tobias, Hitzler, Johann, Roberts, Irene, Vyas, Paresh, Juban, Gaetan, Hennig, Christian, Hansen, Gesine, Li, Zhe, Orkin, Stuart, Reinhardt, Dirk, Klusmann, Jan-Henning
Published 2013

Normal Hematopoietic Progenitor Subsets Have Distinct Reactive Oxygen Species, BCL2 and Cell-Cycle Profiles That Are Decoupled from Maturation in Acute Myeloid Leukemia

by Khan, Naeem, Hills, Robert K., Knapper, Steve, Steadman, Lora, Qureshi, Ushna, Rector, Jerrald L., Bradbury, Charlotte, Russell, Nigel H., Vyas, Paresh, Burnett, Alan K., Grimwade, David, Hole, Paul S., Freeman, Sylvie D.
Published 2016

Tolerability and Clinical Activity of Post-Transplantation Azacitidine in Patients Allografted for Acute Myeloid Leukemia Treated on the RICAZA Trial

by Craddock, Charles, Jilani, Nadira, Siddique, Shamyla, Yap, Christina, Khan, Josephine, Nagra, Sandeep, Ward, Janice, Ferguson, Paul, Hazlewood, Peter, Buka, Richard, Vyas, Paresh, Goodyear, Oliver, Tholouli, Eleni, Crawley, Charles, Russell, Nigel, Byrne, Jenny, Malladi, Ram, Snowden, John, Dennis, Mike
Published 2016

Combining gene mutation with gene expression data improves outcome prediction in myelodysplastic syndromes

by Gerstung, Moritz, Pellagatti, Andrea, Malcovati, Luca, Giagounidis, Aristoteles, Porta, Matteo G Della, Jädersten, Martin, Dolatshad, Hamid, Verma, Amit, Cross, Nicholas C. P., Vyas, Paresh, Killick, Sally, Hellström-Lindberg, Eva, Cazzola, Mario, Papaemmanuil, Elli, Campbell, Peter J., Boultwood, Jacqueline
Published 2015

Prognostic value of monitoring a candidate immunophenotypic leukemic stem/progenitor cell population in patients allografted for acute myeloid leukemia

by Bradbury, Charlotte, Houlton, Aimee E, Akiki, Susanna, Gregg, Richard, Rindl, Max, Khan, Josephine, Ward, Janice, Khan, Naeem, Griffiths, Mike, Nagra, Sandeep, Hills, Robert, Burnett, Alan, Russell, Nigel, Vyas, Paresh, Grimwade, David, Craddock, Charles, Freeman, Sylvie D.
Published 2014

Generation of bivalent chromatin domains during cell fate decisions

by De Gobbi, Marco, Garrick, David, Lynch, Magnus, Vernimmen, Douglas, Hughes, Jim R, Goardon, Nicolas, Luc, Sidinh, Lower, Karen M, Sloane-Stanley, Jacqueline A, Pina, Cristina, Soneji, Shamit, Renella, Raffaele, Enver, Tariq, Taylor, Stephen, Jacobsen, Sten Eirik W, Vyas, Paresh, Gibbons, Richard J, Higgs, Douglas R
Published 2011

FLT3-ITDs Instruct a Myeloid Differentiation and Transformation Bias in Lymphomyeloid Multipotent Progenitors

by Mead, Adam J., Kharazi, Shabnam, Atkinson, Deborah, Macaulay, Iain, Pecquet, Christian, Loughran, Stephen, Lutteropp, Michael, Woll, Petter, Chowdhury, Onima, Luc, Sidinh, Buza-Vidas, Natalija, Ferry, Helen, Clark, Sally-Ann, Goardon, Nicolas, Vyas, Paresh, Constantinescu, Stefan N., Sitnicka, Ewa, Nerlov, Claus, Jacobsen, Sten Eirik W.
Published 2013

Genetically distinct leukemic stem cells in human CD34− acute myeloid leukemia are arrested at a hemopoietic precursor-like stage

by Quek, Lynn, Otto, Georg W., Garnett, Catherine, Lhermitte, Ludovic, Karamitros, Dimitris, Stoilova, Bilyana, Lau, I-Jun, Doondeea, Jessica, Usukhbayar, Batchimeg, Kennedy, Alison, Metzner, Marlen, Goardon, Nicolas, Ivey, Adam, Allen, Christopher, Gale, Rosemary, Davies, Benjamin, Sternberg, Alexander, Killick, Sally, Hunter, Hannah, Cahalin, Paul, Price, Andrew, Carr, Andrew, Griffiths, Mike, Virgo, Paul, Mackinnon, Stephen, Grimwade, David, Freeman, Sylvie, Russell, Nigel, Craddock, Charles, Mead, Adam, Peniket, Andrew, Porcher, Catherine, Vyas, Paresh
Published 2016

Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

by Ju, Young Seok, Alexandrov, Ludmil B, Gerstung, Moritz, Martincorena, Inigo, Nik-Zainal, Serena, Ramakrishna, Manasa, Davies, Helen R, Papaemmanuil, Elli, Gundem, Gunes, Shlien, Adam, Bolli, Niccolo, Behjati, Sam, Tarpey, Patrick S, Nangalia, Jyoti, Massie, Charles E, Butler, Adam P, Teague, Jon W, Vassiliou, George S, Green, Anthony R, Du, Ming-Qing, Unnikrishnan, Ashwin, Pimanda, John E, Teh, Bin Tean, Munshi, Nikhil, Greaves, Mel, Vyas, Paresh, El-Naggar, Adel K, Santarius, Tom, Collins, V Peter, Grundy, Richard, Taylor, Jack A, Hayes, D Neil, Malkin, David, Foster, Christopher S, Warren, Anne Y, Whitaker, Hayley C, Brewer, Daniel, Eeles, Rosalind, Cooper, Colin, Neal, David, Visakorpi, Tapio, Isaacs, William B, Bova, G Steven, Flanagan, Adrienne M, Futreal, P Andrew, Lynch, Andy G, Chinnery, Patrick F, McDermott, Ultan, Stratton, Michael R, Campbell, Peter J
Published 2014

Factors influencing success of clinical genome sequencing across a broad spectrum of disorders

by Taylor, Jenny C, Martin, Hilary C, Lise, Stefano, Broxholme, John, Cazier, Jean-Baptiste, Rimmer, Andy, Kanapin, Alexander, Lunter, Gerton, Fiddy, Simon, Allan, Chris, Aricescu, A. Radu, Attar, Moustafa, Babbs, Christian, Becq, Jennifer, Beeson, David, Bento, Celeste, Bignell, Patricia, Blair, Edward, Buckle, Veronica J, Bull, Katherine, Cais, Ondrej, Cario, Holger, Chapel, Helen, Copley, Richard R, Cornall, Richard, Craft, Jude, Dahan, Karin, Davenport, Emma E, Dendrou, Calliope, Devuyst, Olivier, Fenwick, Aimée L, Flint, Jonathan, Fugger, Lars, Gilbert, Rodney D, Goriely, Anne, Green, Angie, Greger, Ingo H., Grocock, Russell, Gruszczyk, Anja V, Hastings, Robert, Hatton, Edouard, Higgs, Doug, Hill, Adrian, Holmes, Chris, Howard, Malcolm, Hughes, Linda, Humburg, Peter, Johnson, David, Karpe, Fredrik, Kingsbury, Zoya, Kini, Usha, Knight, Julian C, Krohn, Jonathan, Lamble, Sarah, Langman, Craig, Lonie, Lorne, Luck, Joshua, McCarthy, Davis, McGowan, Simon J, McMullin, Mary Frances, Miller, Kerry A, Murray, Lisa, Németh, Andrea H, Nesbit, M Andrew, Nutt, David, Ormondroyd, Elizabeth, Oturai, Annette Bang, Pagnamenta, Alistair, Patel, Smita Y, Percy, Melanie, Petousi, Nayia, Piazza, Paolo, Piret, Sian E, Polanco-Echeverry, Guadalupe, Popitsch, Niko, Powrie, Fiona, Pugh, Chris, Quek, Lynn, Robbins, Peter A, Robson, Kathryn, Russo, Alexandra, Sahgal, Natasha, van Schouwenburg, Pauline A, Schuh, Anna, Silverman, Earl, Simmons, Alison, Sørensen, Per Soelberg, Sweeney, Elizabeth, Taylor, John, Thakker, Rajesh V, Tomlinson, Ian, Trebes, Amy, Twigg, Stephen RF, Uhlig, Holm H, Vyas, Paresh, Vyse, Tim, Wall, Steven A, Watkins, Hugh, Whyte, Michael P, Witty, Lorna, Wright, Ben, Yau, Chris, Buck, David, Humphray, Sean, Ratcliffe, Peter J, Bell, John I, Wilkie, Andrew OM, Bentley, David, Donnelly, Peter, McVean, Gilean
Published 2015