Two phosphatidylinositol 4-kinases control lysosomal delivery of the Gaucher disease enzyme, β-glucocerebrosidase

by Jović, Marko, Kean, Michelle J., Szentpetery, Zsofia, Polevoy, Gordon, Gingras, Anne-Claude, Brill, Julie A., Balla, Tamas
Published 2012

Heart of glass anchors Rasip1 at endothelial cell-cell junctions to support vascular integrity

by de Kreuk, Bart-Jan, Gingras, Alexandre R, Knight, James DR, Liu, Jian J, Gingras, Anne-Claude, Ginsberg, Mark H
Published 2016

A novel whole-cell lysate kinase assay identifies substrates of the p38 MAPK in differentiating myoblasts

by Knight, James DR, Tian, Ruijun, Lee, Robin EC, Wang, Fangjun, Beauvais, Ariane, Zou, Hanfa, Megeney, Lynn A, Gingras, Anne-Claude, Pawson, Tony, Figeys, Daniel, Kothary, Rashmi
Published 2012

SAINT: Probabilistic Scoring of Affinity Purification - Mass Spectrometry Data

by Choi, Hyungwon, Larsen, Brett, Lin, Zhen-Yuan, Breitkreutz, Ashton, Mellacheruvu, Dattatreya, Fermin, Damian, Qin, Zhaohui S., Tyers, Mike, Gingras, Anne-Claude, Nesvizhskii, Alexey I.
Published 2010

Assessing cellular efficacy of bromodomain inhibitors using fluorescence recovery after photobleaching

by Philpott, Martin, Rogers, Catherine M, Yapp, Clarence, Wells, Chris, Lambert, Jean-Philippe, Strain-Damerell, Claire, Burgess-Brown, Nicola A, Gingras, Anne-Claude, Knapp, Stefan, Müller, Susanne
Published 2014

SETD6 controls the expression of estrogen-responsive genes and proliferation of breast carcinoma cells

by O'Neill, Daniel J, Williamson, Stuart Charles, Alkharaif, Dhuha, Monteiro, Isabella Christina Mazzaro, Goudreault, Marilyn, Gaughan, Luke, Robson, Craig N, Gingras, Anne-Claude, Binda, Olivier
Published 2014

Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family

by Filippakopoulos, Panagis, Picaud, Sarah, Mangos, Maria, Keates, Tracy, Lambert, Jean-Philippe, Barsyte-Lovejoy, Dalia, Felletar, Ildiko, Volkmer, Rudolf, Müller, Susanne, Pawson, Tony, Gingras, Anne-Claude, Arrowsmith, Cheryl H., Knapp, Stefan
Published 2012

Proteomic Profiling of the TRAF3 Interactome Network Reveals a New Role for the ER-to-Golgi Transport Compartments in Innate Immunity

by van Zuylen, Wendy J., Doyon, Priscilla, Clément, Jean-François, Khan, Kashif Aziz, D'Ambrosio, Lisa M., Dô, Florence, St-Amant-Verret, Myriam, Wissanji, Tasheen, Emery, Gregory, Gingras, Anne-Claude, Meloche, Sylvain, Servant, Marc J.
Published 2012

Mapping differential interactomes by affinity purification coupled with data independent mass spectrometry acquisition

by Lambert, Jean-Philippe, Ivosev, Gordana, Couzens, Amber L., Larsen, Brett, Taipale, Mikko, Lin, Zhen-Yuan, Zhong, Quan, Lindquist, Susan, Vidal, Marc, Aebersold, Ruedi, Pawson, Tony, Bonner, Ron, Tate, Stephen, Gingras, Anne-Claude
Published 2013

Multivalent Histone and DNA Engagement by a PHD/BRD/PWWP Triple Reader Cassette Recruits ZMYND8 to K14ac-Rich Chromatin

by Savitsky, Pavel, Krojer, Tobias, Fujisawa, Takao, Lambert, Jean-Philippe, Picaud, Sarah, Wang, Chen-Yi, Shanle, Erin K., Krajewski, Krzysztof, Friedrichsen, Hans, Kanapin, Alexander, Goding, Colin, Schapira, Matthieu, Samsonova, Anastasia, Strahl, Brian D., Gingras, Anne-Claude, Filippakopoulos, Panagis
Published 2016

Topoisomerase II beta interacts with cohesin and CTCF at topological domain borders

by Uusküla-Reimand, Liis, Hou, Huayun, Samavarchi-Tehrani, Payman, Rudan, Matteo Vietri, Liang, Minggao, Medina-Rivera, Alejandra, Mohammed, Hisham, Schmidt, Dominic, Schwalie, Petra, Young, Edwin J., Reimand, Jüri, Hadjur, Suzana, Gingras, Anne-Claude, Wilson, Michael D.
Published 2016

SLC25A46 is required for mitochondrial lipid homeostasis and cristae maintenance and is responsible for Leigh syndrome

by Janer, Alexandre, Prudent, Julien, Paupe, Vincent, Fahiminiya, Somayyeh, Majewski, Jacek, Sgarioto, Nicolas, Des Rosiers, Christine, Forest, Anik, Lin, Zhen‐Yuan, Gingras, Anne‐Claude, Mitchell, Grant, McBride, Heidi M, Shoubridge, Eric A
Published 2016

Quantitative analysis of PPT1 interactome in human neuroblastoma cells

by Scifo, Enzo, Szwajda, Agnieszka, Soliymani, Rabah, Pezzini, Francesco, Bianchi, Marzia, Dapkunas, Arvydas, Dębski, Janusz, Uusi-Rauva, Kristiina, Dadlez, Michał, Gingras, Anne-Claude, Tyynelä, Jaana, Simonati, Alessandro, Jalanko, Anu, Baumann, Marc H., Lalowski, Maciej
Published 2015

The linear ubiquitin-specific deubiquitinase Gumby/Fam105b regulates angiogenesis

by Rivkin, Elena, Almeida, Stephanie M., Ceccarelli, Derek F., Juang, Yu-Chi, MacLean, Teresa A., Srikumar, Tharan, Huang, Hao, Dunham, Wade H., Fukumura, Ryutaro, Xie, Gang, Gondo, Yoichi, Raught, Brian, Gingras, Anne-Claude, Sicheri, Frank, Cordes, Sabine P.
Published 2013

Dual Action Antifungal Small Molecule Modulates Multidrug Efflux and TOR Signaling

by Shekhar-Guturja, Tanvi, Gunaherath, G. M. Kamal B., Kithsiri Wijeratne, E. M., Lambert, Jean-Philippe, Averette, Anna F., Lee, Soo Chan, Kim, Taeyup, Bahn, Yong-Sun, Tripodi, Farida, Ammar, Ron, Döhl, Katja, Niewola-Staszkowska, Karolina, Schmitt, Lutz, Loewith, Robbie J., Roth, Frederick P., Sanglard, Dominique, Andes, David, Nislow, Corey, Coccetti, Paola, Gingras, Anne-Claude, Heitman, Joseph, Leslie Gunatilaka, A. A., Cowen, Leah E.
Published 2016

Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia

by Picaud, Sarah, Leonards, Katharina, Lambert, Jean-Philippe, Dovey, Oliver, Wells, Christopher, Fedorov, Oleg, Monteiro, Octovia, Fujisawa, Takao, Wang, Chen-Yi, Lingard, Hannah, Tallant, Cynthia, Nikbin, Nikzad, Guetzoyan, Lucie, Ingham, Richard, Ley, Steven V., Brennan, Paul, Muller, Susanne, Samsonova, Anastasia, Gingras, Anne-Claude, Schwaller, Juerg, Vassiliou, George, Knapp, Stefan, Filippakopoulos, Panagis
Published 2016

Temporal regulation of EGF signaling networks by the scaffold protein Shc1

by Zheng, Yong, Zhang, Cunjie, Croucher, David R., Soliman, Mohamed A., St-Denis, Nicole, Pasculescu, Adrian, Taylor, Lorne, Tate, Stephen A., Hardy, Rod W., Colwill, Karen, Dai, Anna Yue, Bagshaw, Rick, Dennis, James W., Gingras, Anne-Claude, Daly, Roger J., Pawson, Tony
Published 2013

Construction of human activity-based phosphorylation networks

by Newman, Robert H, Hu, Jianfei, Rho, Hee-Sool, Xie, Zhi, Woodard, Crystal, Neiswinger, John, Cooper, Christopher, Shirley, Matthew, Clark, Hillary M, Hu, Shaohui, Hwang, Woochang, Seop Jeong, Jun, Wu, George, Lin, Jimmy, Gao, Xinxin, Ni, Qiang, Goel, Renu, Xia, Shuli, Ji, Hongkai, Dalby, Kevin N, Birnbaum, Morris J, Cole, Philip A, Knapp, Stefan, Ryazanov, Alexey G, Zack, Donald J, Blackshaw, Seth, Pawson, Tony, Gingras, Anne-Claude, Desiderio, Stephen, Pandey, Akhilesh, Turk, Benjamin E, Zhang, Jin, Zhu, Heng, Qian, Jiang
Published 2013

The CRAPome: a Contaminant Repository for Affinity Purification Mass Spectrometry Data

by Mellacheruvu, Dattatreya, Wright, Zachary, Couzens, Amber L., Lambert, Jean-Philippe, St-Denis, Nicole, Li, Tuo, Miteva, Yana V., Hauri, Simon, Sardiu, Mihaela E., Low, Teck Yew, Halim, Vincentius A., Bagshaw, Richard D., Hubner, Nina C., al-Hakim, Abdallah, Bouchard, Annie, Faubert, Denis, Fermin, Damian, Dunham, Wade H., Goudreault, Marilyn, Lin, Zhen-Yuan, Badillo, Beatriz Gonzalez, Pawson, Tony, Durocher, Daniel, Coulombe, Benoit, Aebersold, Ruedi, Superti-Furga, Giulio, Colinge, Jacques, Heck, Albert J. R., Choi, Hyungwon, Gstaiger, Matthias, Mohammed, Shabaz, Cristea, Ileana M., Bennett, Keiryn L., Washburn, Mike P., Raught, Brian, Ewing, Rob M., Gingras, Anne-Claude, Nesvizhskii, Alexey I.
Published 2013