Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia

Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia

BET bromodomains are unique targeting modules that mediate primary transcription response.

Bibliographic Details
Main Authors: Picaud, Sarah, Leonards, Katharina, Lambert, Jean-Philippe, Dovey, Oliver, Wells, Christopher, Fedorov, Oleg, Monteiro, Octovia, Fujisawa, Takao, Wang, Chen-Yi, Lingard, Hannah, Tallant, Cynthia, Nikbin, Nikzad, Guetzoyan, Lucie, Ingham, Richard, Ley, Steven V., Brennan, Paul, Muller, Susanne, Samsonova, Anastasia, Gingras, Anne-Claude, Schwaller, Juerg, Vassiliou, George, Knapp, Stefan, Filippakopoulos, Panagis
Format: Online
Language:English
Published: American Association for the Advancement of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061470/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061470/

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