Local amplification of glucocorticoids in the aging brain and impaired spatial memory

by Yau, Joyce L. W., Seckl, Jonathan R.
Published 2012

11β-Hydroxysteroid dehydrogenases and the brain: From zero to hero, a decade of progress

by Wyrwoll, Caitlin S., Holmes, Megan C., Seckl, Jonathan R.
Published 2011

Response to Comment on: Turban et al. Optimal Elevation of β-Cell 11β-Hydroxysteroid Dehydrogenase Type 1 Is a Compensatory Mechanism That Prevents High-Fat Diet–Induced β-Cell Fai...

by Turban, Sophie, Seckl, Jonathan R., Morton, Nicholas M.
Published 2012

Prenatal dexamethasone ‘programmes’ hypotension, but stress-induced hypertension in adult offspring

by O'Regan, David, Kenyon, Christopher J, Seckl, Jonathan R, Holmes, Megan C
Published 2008

Modulation of 11β-Hydroxysteroid Dehydrogenase as a Strategy to Reduce Vascular Inflammation

by Hadoke, Patrick W. F., Kipari, Tiina, Seckl, Jonathan R., Chapman, Karen E.
Published 2013

Juvenile stress enhances anxiety and alters corticosteroid receptor expression in adulthood

by Brydges, Nichola M, Jin, Rowen, Seckl, Jonathan, Holmes, Megan C, Drake, Amanda J, Hall, Jeremy
Published 2014

Changing glucocorticoid action: 11β-Hydroxysteroid dehydrogenase type 1 in acute and chronic inflammation

by Chapman, Karen E., Coutinho, Agnes E., Zhang, Zhenguang, Kipari, Tiina, Savill, John S., Seckl, Jonathan R.
Published 2013

Diurnal and stress‐induced intra‐hippocampal corticosterone rise attenuated in 11β‐HSD1‐deficient mice: a microdialysis study in young and aged mice

by Yau, Joyce L. W., Noble, June, Kenyon, Christopher J., Ludwig, Mike, Seckl, Jonathan R.
Published 2015

Placental 5-methylcytosine and 5-hydroxymethylcytosine patterns associate with size at birth

by Piyasena, Chinthika, Reynolds, Rebecca M, Khulan, Batbayar, Seckl, Jonathan R, Menon, Gopi, Drake, Amanda J
Published 2015

Post-weaning diet determines metabolic risk in mice exposed to overnutrition in early life

by King, Vicky, Norman, Jane E, Seckl, Jonathan R, Drake, Amanda J
Published 2014

Peripheral mechanisms contributing to the glucocorticoid hypersensitivity in proopiomelanocortin null mice treated with corticosterone

by Michailidou, Zoi, Coll, Anthony P, Kenyon, Christopher J, Morton, Nicholas M, O'Rahilly, Stephen, Seckl, Jonathan R, Chapman, Karen E
Published 2007

Stable conditional expression and effect of C/EBPβ-LIP in adipocytes using the pSLIK system

by Esteves, Cristina L, Kelly, Val, Bégay, Valérie, Lillico, Simon G, Leutz, Achim, Seckl, Jonathan R, Chapman, Karen E
Published 2013

24S,25-Epoxycholesterol in mouse and rat brain

by Wang, Yuchen, Karu, Kersti, Meljon, Anna, Turton, John, Yau, Joyce L., Seckl, Jonathan R., Wang, Yuqin, Griffiths, William J.
Published 2014

11β-hydroxysteroid dehydrogenase-1 deficiency alters the gut microbiome response to Western diet

by Johnson, Jethro S, Opiyo, Monica N, Thomson, Marian, Gharbi, Karim, Seckl, Jonathan R, Heger, Andreas, Chapman, Karen E
Published 2016

Overexpression of mineralocorticoid receptors does not affect memory and anxiety-like behavior in female mice

by Kanatsou, Sofia, Kuil, Laura E., Arp, Marit, Oitzl, Melly S., Harris, Anjanette P., Seckl, Jonathan R., Krugers, Harm J., Joels, Marian
Published 2015

Effects of Mineralocorticoid Receptor Overexpression on Anxiety and Memory after Early Life Stress in Female Mice

by Kanatsou, Sofia, Ter Horst, Judith P., Harris, Anjanette P., Seckl, Jonathan R., Krugers, Harmen J., Joëls, Marian
Published 2016

11β-Hydroxysteroid Dehydrogenase Type 1, But Not Type 2, Deficiency Worsens Acute Inflammation and Experimental Arthritis in Mice

by Coutinho, Agnes E., Gray, Mohini, Brownstein, David G., Salter, Donald M., Sawatzky, Deborah A., Clay, Spike, Gilmour, James S., Seckl, Jonathan R., Savill, John S., Chapman, Karen E.
Published 2012

Optimal Elevation of β-Cell 11β-Hydroxysteroid Dehydrogenase Type 1 Is a Compensatory Mechanism That Prevents High-Fat Diet–Induced β-Cell Failure

by Turban, Sophie, Liu, Xiaoxia, Ramage, Lynne, Webster, Scott P., Walker, Brian R., Dunbar, Donald R., Mullins, John J., Seckl, Jonathan R., Morton, Nicholas M.
Published 2012

Regulation of Adipocyte 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) by CCAAT/Enhancer-Binding Protein (C/EBP) β Isoforms, LIP and LAP

by Esteves, Cristina L., Kelly, Val, Bégay, Valérie, Man, Tak Y., Morton, Nicholas M., Leutz, Achim, Seckl, Jonathan R., Chapman, Karen E.
Published 2012

Salicylate Downregulates 11β-HSD1 Expression in Adipose Tissue in Obese Mice and in Humans, Mediating Insulin Sensitization

by Nixon, Mark, Wake, Deborah J., Livingstone, Dawn E., Stimson, Roland H., Esteves, Cristina L., Seckl, Jonathan R., Chapman, Karen E., Andrew, Ruth, Walker, Brian R.
Published 2012