Optimal Elevation of β-Cell 11β-Hydroxysteroid Dehydrogenase Type 1 Is a Compensatory Mechanism That Prevents High-Fat Diet–Induced β-Cell Failure

by Turban, Sophie, Liu, Xiaoxia, Ramage, Lynne, Webster, Scott P., Walker, Brian R., Dunbar, Donald R., Mullins, John J., Seckl, Jonathan R., Morton, Nicholas M.
Published 2012

β-Cell-Specific Glucocorticoid Reactivation Attenuates Inflammatory β-Cell Destruction

by Liu, Xiaoxia, Turban, Sophie, Carter, Roderick N., Ahmad, Shakil, Ramage, Lynne, Webster, Scott P., Walker, Brian R., Seckl, Jonathan R., Morton, Nicholas M.
Published 2014

Novel Fat Depot–Specific Mechanisms Underlie Resistance to Visceral Obesity and Inflammation in 11β-Hydroxysteroid Dehydrogenase Type 1–Deficient Mice

by Wamil, Malgorzata, Battle, Jenny H., Turban, Sophie, Kipari, Tiina, Seguret, David, de Sousa Peixoto, Ricardo, Nelson, Yvonne B., Nowakowska, Dominika, Ferenbach, David, Ramage, Lynne, Chapman, Karen E., Hughes, Jeremy, Dunbar, Donald R., Seckl, Jonathan R., Morton, Nicholas M.
Published 2011

A Stratified Transcriptomics Analysis of Polygenic Fat and Lean Mouse Adipose Tissues Identifies Novel Candidate Obesity Genes

by Morton, Nicholas M., Nelson, Yvonne B., Michailidou, Zoi, Di Rollo, Emma M., Ramage, Lynne, Hadoke, Patrick W. F., Seckl, Jonathan R., Bunger, Lutz, Horvat, Simon, Kenyon, Christopher J., Dunbar, Donald R.
Published 2011

Glucocorticoids Acutely Increase Brown Adipose Tissue Activity in Humans, Revealing Species-Specific Differences in UCP-1 Regulation

by Ramage, Lynne E., Akyol, Murat, Fletcher, Alison M., Forsythe, John, Nixon, Mark, Carter, Roderick N., van Beek, Edwin J.R., Morton, Nicholas M., Walker, Brian R., Stimson, Roland H.
Published 2016