24S,25-Epoxycholesterol in mouse and rat brain
•24S,25-Epoxycholesterol identified and quantified in rodent brain.•Knock out of Cyp27a1 leads to a decrease in 24S,25-epoxycholesterol.•Knock out of Cyp7b1 leads to an increase in 24S,25-epoxycholesterol.•24S,25-Epoxycholesterol is metabolised by Cyp7b1 but not Cyp27a1.
| Main Authors: | , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Academic Press
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053837/ |