Analysis of Tumor Heterogeneity and Cancer Gene Networks Using Deep Sequencing of MMTV-Induced Mouse Mammary Tumors

Cancer develops through a multistep process in which normal cells progress to malignant tumors via the evolution of their genomes as a result of the acquisition of mutations in cancer driver genes. The number, identity and mode of action of cancer driver genes, and how they contribute to tumor evolu...

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Bibliographic Details
Main Authors: Klijn, Christiaan, Koudijs, Marco J., Kool, Jaap, ten Hoeve, Jelle, Boer, Mandy, de Moes, Joost, Akhtar, Waseem, van Miltenburg, Martine, Vendel-Zwaagstra, Annabel, Reinders, Marcel J. T., Adams, David J., van Lohuizen, Maarten, Hilkens, John, Wessels, Lodewyk F. A., Jonkers, Jos
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653918/