Identification of cancer genes using a statistical framework for multiexperiment analysis of nondiscretized array CGH data

Tumor formation is in part driven by DNA copy number alterations (CNAs), which can be measured using microarray-based Comparative Genomic Hybridization (aCGH). Multiexperiment analysis of aCGH data from tumors allows discovery of recurrent CNAs that are potentially causal to cancer development. Unti...

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Bibliographic Details
Main Authors: Klijn, Christiaan, Holstege, Henne, de Ridder, Jeroen, Liu, Xiaoling, Reinders, Marcel, Jonkers, Jos, Wessels, Lodewyk
Format: Online
Language:English
Published: Oxford University Press 2008
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241875/