Rapid validation of cancer genes in chimeras derived from established genetically engineered mouse models
Recent technological advances have opened the door for the fast and cost-effective generation of genetically engineered mouse models (GEMMs) to study cancer. We describe here a conceptually novel approach for the generation of chimeric GEMMs based on the controlled introduction of various genetic el...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
WILEY-VCH Verlag
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179600/ |