Bromodomains as therapeutic targets
Acetylation of lysine residues is a post-translational modification with broad relevance to cellular signalling and disease biology. Enzymes that ‘write’ (histone acetyltransferases, HATs) and ‘erase’ (histone deacetylases, HDACs) acetylation sites are an area of extens...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
Cambridge University Press
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177561/ |