Crotamine stimulates phagocytic activity by inducing nitric oxide and TNF-α via p38 and NFκ-B signaling in RAW 264.7 macrophages
Crotamine is a peptide toxin found in the venom of the rattlesnake Crotalus durissus terrificus and has antiproliferative, antimicrobial, and antifungal activities. Herein, we show that crotamine dose-dependently induced macrophage phagocytic and cytostatic activity by the induction of nitric oxide...
Main Authors: | Lee, Kyung Jin, Kim, Yun Kyu, Krupa, Martin, Nguyen, Anh Ngoc, Do, Bich Hang, Chung, Boram, Vu, Thi Thu Trang, Kim, Song Cheol, Choe, Han |
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Format: | Online |
Language: | English |
Published: |
Korean Society for Biochemistry and Molecular Biology
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915234/ |
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