Genistein Inhibits Osteoclastic Differentiation of RAW 264.7 Cells via Regulation of ROS Production and Scavenging

Genistein, a phytoestrogen, has been demonstrated to have a bone-sparing and antiresorptive effect. Genistein can inhibit the osteoclast formation of receptor activator of nuclear factor-κB ligand (RANKL)-induced RAW 264.7 cells by preventing the translocation of nuclear factor-κB (NF-κB), a redox-s...

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Bibliographic Details
Main Authors: Lee, Sang-Hyun, Kim, Jin-Kyoung, Jang, Hae-Dong
Format: Online
Language:English
Published: MDPI 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100171/