Crotamine stimulates phagocytic activity by inducing nitric oxide and TNF-α via p38 and NFκ-B signaling in RAW 264.7 macrophages

Crotamine stimulates phagocytic activity by inducing nitric oxide and TNF-α via p38 and NFκ-B signaling in RAW 264.7 macrophages

Crotamine is a peptide toxin found in the venom of the rattlesnake Crotalus durissus terrificus and has antiproliferative, antimicrobial, and antifungal activities. Herein, we show that crotamine dose-dependently induced macrophage phagocytic and cytostatic activity by the induction of nitric oxide...

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Bibliographic Details
Main Authors: Lee, Kyung Jin, Kim, Yun Kyu, Krupa, Martin, Nguyen, Anh Ngoc, Do, Bich Hang, Chung, Boram, Vu, Thi Thu Trang, Kim, Song Cheol, Choe, Han
Format: Online
Language:English
Published: Korean Society for Biochemistry and Molecular Biology 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915234/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915234/

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