Regulation of Monoclonal Antibody Immunotherapy by FcγRIIB
Monoclonal antibodies (mAb) are revolutionising the treatment of many different diseases. Given their differing mode of action compared to most conventional chemotherapeutics and small molecule inhibitors, they possess the potential to be independent of common modes of treatment resistance and can t...
Main Authors: | Stopforth, Richard J., Cleary, Kirstie L. S., Cragg, Mark S. |
---|---|
Format: | Online |
Language: | English |
Published: |
Springer US
2016
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891381/ |
Similar Items
-
Functional Role of FcγRIIB in the Regulation of Mesenchymal Stem Cell Function
by: Zhu, Tianyi, et al.
Published: (2016) -
Genetic Modifiers of Systemic Lupus Erythematosus in FcγRIIB−/− Mice
by: Bolland, Silvia, et al.
Published: (2002) -
High synovial expression of the inhibitory FcγRIIb in rheumatoid arthritis
by: Magnusson, Sofia E, et al.
Published: (2007) -
IgG-Independent Co-aggregation of FcεRI and FcγRIIB Results in LYN- and SHIP1-Dependent Tyrosine Phosphorylation of FcγRIIB in Murine Bone Marrow-Derived Mast Cells
by: Mathias Gast, et al.
Published: (2018-08-01) -
Engineered antibody Fc variant with selectively enhanced FcγRIIb binding over both FcγRIIaR131 and FcγRIIaH131
by: Mimoto, F., et al.
Published: (2013)