Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program

Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program

The ability of dendritic cells (DCs) to activate immunity is linked to their maturation status. In prior studies, we have shown that selective antibody-mediated blockade of inhibitory FcγRIIB receptor on human DCs in the presence of activating immunoglobulin (Ig) ligands leads to DC maturation and e...

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Bibliographic Details
Main Authors: Dhodapkar, Kavita M., Banerjee, Devi, Connolly, John, Kukreja, Anjli, Matayeva, Elyana, Veri, Maria Concetta, Ravetch, Jeffrey V., Steinman, Ralph M., Dhodapkar, Madhav V.
Format: Online
Language:English
Published: The Rockefeller University Press 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118610/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118610/

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