Impairment on the lateral mobility induced by structural changes underlies the functional deficiency of the lupus-associated polymorphism FcγRIIB-T232

Impairment on the lateral mobility induced by structural changes underlies the functional deficiency of the lupus-associated polymorphism FcγRIIB-T232

Xu et al. show that the lupus-associated polymorphism FcγRIIB-T232 has structural changes of the TM domain that reduces lateral mobility and inhibitory functions.

Bibliographic Details
Main Authors: Xu, Liling, Xia, Mengdie, Guo, Jun, Sun, Xiaolin, Li, Hua, Xu, Chenguang, Gu, Xiaomei, Zhang, Haowen, Yi, Junyang, Fang, Yan, Xie, Hengyi, Wang, Jing, Shen, Zhixun, Xue, Boxin, Sun, Yujie, Meckel, Tobias, Chen, Ying-Hua, Hu, Zhibin, Li, Zhanguo, Xu, Chenqi, Gong, Haipeng, Liu, Wanli
Format: Online
Language:English
Published: The Rockefeller University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110019/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110019/

Similar Items