Human antibodies induce arthritis in mice deficient in the low-affinity inhibitory IgG receptor FcγRIIB
Rheumatoid arthritis (RA) is a complex autoimmune disease with a poorly understood pathogenesis. The disease is associated with polyclonal B cell activation and the production of autoantibodies (autoAbs), but there is a longstanding controversy as to whether such Abs contribute to, or are secondary...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2006
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118221/ |