The Nuclear Orphan Receptor NR4A1 is Involved in the Apoptotic Pathway Induced by LPS and Simvastatin in RAW 264.7 Macrophages

The Nuclear Orphan Receptor NR4A1 is Involved in the Apoptotic Pathway Induced by LPS and Simvastatin in RAW 264.7 Macrophages

Macrophage death plays a role in several physiological and inflammatory pathologies such as sepsis and arthritis. In our previous work, we showed that simvastatin triggers cell death in LPS-activated RAW 264.7 mouse macrophage cells through both caspase-dependent and independent apoptotic pathways....

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Bibliographic Details
Main Authors: Kim, Yong Chan, Song, Seok Bean, Lee, Sang Kyu, Park, Sang Min, Kim, Young Sang
Format: Online
Language:English
Published: The Korean Association of Immunologists 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022779/

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