The Nuclear Orphan Receptor NR4A1 is Involved in the Apoptotic Pathway Induced by LPS and Simvastatin in RAW 264.7 Macrophages

Macrophage death plays a role in several physiological and inflammatory pathologies such as sepsis and arthritis. In our previous work, we showed that simvastatin triggers cell death in LPS-activated RAW 264.7 mouse macrophage cells through both caspase-dependent and independent apoptotic pathways....

Full description

Bibliographic Details
Main Authors: Kim, Yong Chan, Song, Seok Bean, Lee, Sang Kyu, Park, Sang Min, Kim, Young Sang
Format: Online
Language:English
Published: The Korean Association of Immunologists 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022779/