Activation of executioner caspases is a predictor of progression-free survival in glioblastoma patients: a systems medicine approach

Activation of executioner caspases is a predictor of progression-free survival in glioblastoma patients: a systems medicine approach

Glioblastoma (GBM) is the most common and aggressive primary brain tumor in adults. GBM cells are highly resistant to apoptosis induced by antitumor drugs and radiotherapy resulting in cancer progression. We assessed whether a systems medicine approach, analysing the ability of tumor cells to execut...

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Bibliographic Details
Main Authors: Murphy, Á C, Weyhenmeyer, B, Schmid, J, Kilbride, S M, Rehm, M, Huber, H J, Senft, C, Weissenberger, J, Seifert, V, Dunst, M, Mittelbronn, M, Kögel, D, Prehn, J H M, Murphy, B M
Format: Online
Language:English
Published: Nature Publishing Group 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674364/

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