Latrepirdine is a potent activator of AMP-activated protein kinase and reduces neuronal excitability

Latrepirdine/Dimebon is a small-molecule compound with attributed neurocognitive-enhancing activities, which has recently been tested in clinical trials for the treatment of Alzheimer's and Huntington's disease. Latrepirdine has been suggested to be a neuroprotective agent that increases m...

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Bibliographic Details
Main Authors: Weisová, P, Alvarez, S P, Kilbride, S M, Anilkumar, U, Baumann, B, Jordán, J, Bernas, T, Huber, H J, Düssmann, H, Prehn, J H M
Format: Online
Language:English
Published: Nature Publishing Group 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818013/