Modulation of Mcl-1 sensitizes glioblastoma to TRAIL-induced apoptosis
Glioblastoma (GBM) is the most aggressive form of primary brain tumour, with dismal patient outcome. Treatment failure is associated with intrinsic or acquired apoptosis resistance and the presence of a highly tumourigenic subpopulation of cancer cells called GBM stem cells. Tumour necrosis factor-r...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Springer US
2013
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938842/ |