Executioner Caspase-3 and 7 Deficiency Reduces Myocyte Number in the Developing Mouse Heart

Executioner caspase-3 and -7 are proteases promoting cell death but non-apoptotic roles are being discovered. The heart expresses caspases only during development, suggesting they contribute to the organ maturation process. Therefore, we aimed at identifying novel functions of caspases in heart deve...

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Bibliographic Details
Main Authors: Cardona, Maria, López, Juan Antonio, Serafín, Anna, Rongvaux, Anthony, Inserte, Javier, García-Dorado, David, Flavell, Richard, Llovera, Marta, Cañas, Xavier, Vázquez, Jesús, Sanchis, Daniel
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487935/