The Central Executioner of Apoptosis: Multiple Connections between Protease Activation and Mitochondria in Fas/APO-1/CD95- and Ceramide-induced Apoptosis

The Central Executioner of Apoptosis: Multiple Connections between Protease Activation and Mitochondria in Fas/APO-1/CD95- and Ceramide-induced Apoptosis

According to current understanding, cytoplasmic events including activation of protease cascades and mitochondrial permeability transition (PT) participate in the control of nuclear apoptosis. However, the relationship between protease activation and PT has remained elusive. When apoptosis is induce...

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Bibliographic Details
Main Authors: Susin, Santos A., Zamzami, Naoufal, Castedo, Maria, Daugas, Eric, Wang, Hong-Gang, Geley, Stephan, Fassy, Florence, Reed, John C., Kroemer, Guido
Format: Online
Language:English
Published: The Rockefeller University Press 1997
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2198951/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2198951/

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