Sequencing of Pax6 Loci from the Elephant Shark Reveals a Family of Pax6 Genes in Vertebrate Genomes, Forged by Ancient Duplications and Divergences

Sequencing of Pax6 Loci from the Elephant Shark Reveals a Family of Pax6 Genes in Vertebrate Genomes, Forged by Ancient Duplications and Divergences

Pax6 is a developmental control gene essential for eye development throughout the animal kingdom. In addition, Pax6 plays key roles in other parts of the CNS, olfactory system, and pancreas. In mammals a single Pax6 gene encoding multiple isoforms delivers these pleiotropic functions. Here we provi...

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Bibliographic Details
Main Authors: Ravi, Vydianathan, Bhatia, Shipra, Gautier, Philippe, Loosli, Felix, Tay, Boon-Hui, Tay, Alice, Murdoch, Emma, Coutinho, Pedro, van Heyningen, Veronica, Brenner, Sydney, Venkatesh, Byrappa, Kleinjan, Dirk A.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554528/

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