DNaseI Hypersensitivity and Ultraconservation Reveal Novel, Interdependent Long-Range Enhancers at the Complex Pax6 Cis-Regulatory Region

by McBride, David J., Buckle, Adam, van Heyningen, Veronica, Kleinjan, Dirk A.
Published 2011

The Developmental Regulator Pax6 Is Essential for Maintenance of Islet Cell Function in the Adult Mouse Pancreas

by Hart, Alan W., Mella, Sebastien, Mendrychowski, Jacek, van Heyningen, Veronica, Kleinjan, Dirk A.
Published 2013

Genomic profiling of type-1 adult diabetic and aged normoglycemic mouse liver

by Ghiraldini, Flávia G, Silveira, André B, Kleinjan, Dirk A, Gilbert, Nick, Mello, Maria Luiza S
Published 2014

Identification of Genomic Regions Regulating Pax6 Expression in Embryonic Forebrain Using YAC Reporter Transgenic Mouse Lines

by Mi, Da, Huang, Yu-Ting, Kleinjan, Dirk A., Mason, John O., Price, David J.
Published 2013

Functional conservation of Pax6 regulatory elements in humans and mice demonstrated with a novel transgenic reporter mouse

by Tyas, David A, Simpson, T Ian, Carr, Catherine B, Kleinjan, Dirk A, van Heyningen, Veronica, Mason, John O, Price, David J
Published 2006

Subfunctionalization of Duplicated Zebrafish pax6 Genes by cis-Regulatory Divergence

by Kleinjan, Dirk A, Bancewicz, Ruth M, Gautier, Philippe, Dahm, Ralf, Schonthaler, Helia B, Damante, Giuseppe, Seawright, Anne, Hever, Ann M, Yeyati, Patricia L, van Heyningen, Veronica, Coutinho, Pedro
Published 2008

Sequencing of Pax6 Loci from the Elephant Shark Reveals a Family of Pax6 Genes in Vertebrate Genomes, Forged by Ancient Duplications and Divergences

by Ravi, Vydianathan, Bhatia, Shipra, Gautier, Philippe, Loosli, Felix, Tay, Boon-Hui, Tay, Alice, Murdoch, Emma, Coutinho, Pedro, van Heyningen, Veronica, Brenner, Sydney, Venkatesh, Byrappa, Kleinjan, Dirk A.
Published 2013

Functional Assessment of Disease-Associated Regulatory Variants In Vivo Using a Versatile Dual Colour Transgenesis Strategy in Zebrafish

by Bhatia, Shipra, Gordon, Christopher T., Foster, Robert G., Melin, Lucie, Abadie, Véronique, Baujat, Geneviève, Vazquez, Marie-Paule, Amiel, Jeanne, Lyonnet, Stanislas, van Heyningen, Veronica, Kleinjan, Dirk A.
Published 2015

Disruption of SATB2 or its long-range cis-regulation by SOX9 causes a syndromic form of Pierre Robin sequence

by Rainger, Jacqueline K., Bhatia, Shipra, Bengani, Hemant, Gautier, Philippe, Rainger, Joe, Pearson, Matt, Ansari, Morad, Crow, Jayne, Mehendale, Felicity, Palinkasova, Bozena, Dixon, Michael J., Thompson, Pamela J., Matarin, Mar, Sisodiya, Sanjay M., Kleinjan, Dirk A., FitzPatrick, David R.
Published 2014

Remotely acting SMCHD1 gene regulatory elements: in silico prediction and identification of potential regulatory variants in patients with FSHD

by Mayes, Mary B., Morgan, Taniesha, Winston, Jincy, Buxton, Daniel S., Kamat, Mihir Anant, Smith, Debbie, Williams, Maggie, Martin, Rebecca L., Kleinjan, Dirk A., Cooper, David N., Upadhyaya, Meena, Chuzhanova, Nadia
Published 2015