Distinct roles for Pax7 and Pax3 in adult regenerative myogenesis

We assessed viable Pax7 − / − mice in 129Sv/J background and observed reduced growth and marked muscle wasting together with a complete absence of functional satellite cells. Acute injury resulted in an extreme deficit in muscle regeneration. However, a small number of regenerated myofibers were det...

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Bibliographic Details
Main Authors: Kuang, Shihuan, Chargé, Sophie B., Seale, Patrick, Huh, Michael, Rudnicki, Michael A.
Format: Online
Language:English
Published: The Rockefeller University Press 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063538/