The MH1 domain of Smad3 interacts with Pax6 and represses autoregulation of the Pax6 P1 promoter

Pax6 transcription is under the control of two main promoters (P0 and P1), and these are autoregulated by Pax6. Additionally, Pax6 expression is under the control of the TGFβ superfamily, although the precise mechanisms of such regulation are not understood. The effect of TGFβ on Pax6 expression was...

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Bibliographic Details
Main Authors: Grocott, Timothy, Frost, Victoria, Maillard, Marjorie, Johansen, Terje, Wheeler, Grant N., Dawes, Lucy J., Wormstone, I. Michael, Chantry, Andrew
Format: Online
Language:English
Published: Oxford University Press 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1807973/