Subfunctionalization of Duplicated Zebrafish pax6 Genes by cis-Regulatory Divergence
Gene duplication is a major driver of evolutionary divergence. In most vertebrates a single PAX6 gene encodes a transcription factor required for eye, brain, olfactory system, and pancreas development. In zebrafish, following a postulated whole-genome duplication event in an ancestral teleost, dupli...
Main Authors: | , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Public Library of Science
2008
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242813/ |