Subfunctionalization of Duplicated Zebrafish pax6 Genes by cis-Regulatory Divergence

Gene duplication is a major driver of evolutionary divergence. In most vertebrates a single PAX6 gene encodes a transcription factor required for eye, brain, olfactory system, and pancreas development. In zebrafish, following a postulated whole-genome duplication event in an ancestral teleost, dupli...

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Bibliographic Details
Main Authors: Kleinjan, Dirk A, Bancewicz, Ruth M, Gautier, Philippe, Dahm, Ralf, Schonthaler, Helia B, Damante, Giuseppe, Seawright, Anne, Hever, Ann M, Yeyati, Patricia L, van Heyningen, Veronica, Coutinho, Pedro
Format: Online
Language:English
Published: Public Library of Science 2008
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242813/