Neural precursor cells induce cell death of high-grade astrocytomas via stimulation of TRPV1

Neural precursor cells induce cell death of high-grade astrocytomas via stimulation of TRPV1

Primary astrocytomas of World Health Organization grade 3 and grade 4 (HG-astrocytomas) are preponderant among adults and are almost invariably fatal despite multimodal therapy. Here, we show that the juvenile brain has an endogenous defense mechanism against HG-astrocytomas. Neural precursor cells...

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Bibliographic Details
Main Authors: Stock, Kristin, Kumar, Jitender, Synowitz, Michael, Petrosino, Stefania, Imperatore, Roberta, Smith, Ewan St. J., Wend, Peter, Purfürst, Bettina, Nuber, Ulrike A., Gurok, Ulf, Matyash, Vitali, Wälzlein, Joo-Hee, Chirasani, Sridhar R., Dittmar, Gunnar, Cravatt, Benjamin F., Momma, Stefan, Lewin, Gary R., Ligresti, Alessia, De Petrocellis, Luciano, Cristino, Luigia, Di Marzo, Vincenzo, Kettenmann, Helmut, Glass, Rainer
Format: Online
Language:English
Published: 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480991/

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