Integrated Analysis of Mismatch Repair System in Malignant Astrocytomas

Malignant astrocytomas are the most aggressive primary brain tumors with a poor prognosis despite optimal treatment. Dysfunction of mismatch repair (MMR) system accelerates the accumulation of mutations throughout the genome causing uncontrolled cell growth. The aim of this study was to characterize...

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Bibliographic Details
Main Authors: Rodríguez-Hernández, Irene, Garcia, Juan Luis, Santos-Briz, Angel, Hernández-Laín, Aurelio, González-Valero, Jose María, Gómez-Moreta, Juan Antonio, Toldos-González, Oscar, Cruz, Juan Jesús, Martin-Vallejo, Javier, González-Sarmiento, Rogelio
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779191/