MAPK pathway activation in pilocytic astrocytoma

Pilocytic astrocytoma (PA) is the most common tumor of the pediatric central nervous system (CNS). A body of research over recent years has demonstrated a key role for mitogen-activated protein kinase (MAPK) pathway signaling in the development and behavior of PAs. Several mechanisms lead to activat...

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Bibliographic Details
Main Authors: Jones, David T. W., Gronych, Jan, Lichter, Peter, Witt, Olaf, Pfister, Stefan M.
Format: Online
Language:English
Published: SP Birkhäuser Verlag Basel 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350769/