Targeting Costimulatory Molecules to Improve Antitumor Immunity

Targeting Costimulatory Molecules to Improve Antitumor Immunity

The full activation of T cells necessitates the concomitant activation of two signals, the engagement of T-cell receptor by peptide/major histocompatibility complex II and an additional signal delivered by costimulatory molecules. The best characterized costimulatory molecules belong to B7/CD28 and...

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Bibliographic Details
Main Authors:	Capece, Daria, Verzella, Daniela, Fischietti, Mariafausta, Zazzeroni, Francesca, Alesse, Edoardo
Format:	Online
Language:	English
Published:	Hindawi Publishing Corporation 2012
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303883/

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