Heat-stable antigen is a costimulatory molecule for CD4 T cell growth
Optimal induction of clonal expansion by normal CD4 T cells requires a ligand that can engage the T cell receptor as well as functionally defined costimulatory activity on the same antigen-presenting cell surface. While the presence of effective costimulation induces proliferation, T cell receptor l...
| Format: | Online |
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| Language: | English |
| Published: |
The Rockefeller University Press
1992
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2119117/ |